Hepatic Tumor Radioembolization
Injection of radioactive microspheres (yttrium-90) into the hepatic arteries to deliver targeted radiation to liver tumors.
Hepatic Tumor Radioembolization
Synonyms : selective internal radiation therapy, SIRT
Background and indications
Radioembolization is offered for liver tumors (hepatocellular carcinoma, metastases, cholangiocarcinoma) when other treatments are not suitable. It can also serve as a bridge before transplantation or surgery.
Benefits
This treatment delivers a high radiation dose directly to the tumor with limited effect on surrounding healthy liver. It is generally well tolerated with few side effects.
Procedure
Treatment occurs in two stages. During the first session (work-up), an angiogram maps the hepatic vessels and a test product is injected to simulate treatment. If results are favorable, radioactive microspheres are injected during a second session 1-2 weeks later. Each session lasts approximately 1-2 hours.
Risks
Side effects are generally mild: fatigue, mild abdominal pain. Rarer complications include digestive ulcers (if microspheres migrate to the stomach), liver damage or radiation pneumonitis.
Recovery and follow-up
Each session requires one overnight stay. A CT or MRI is performed 3 months after treatment to assess tumor response.
Practical information
Local anesthesia. Hospital stay: one night.
Français
English