Percutaneous Intralesional Therapeutic Agent Injection

Direct injection of a therapeutic agent into a tumor under image guidance.

Interventional Oncology

Percutaneous Intralesional Therapeutic Agent Injection

Synonyms : image-guided intralesional injection, percutaneous intratumoral injection

Background and indications

Certain experimental or targeted anticancer treatments can be injected directly into a tumor to maximize local concentration while limiting systemic side effects. This includes local immunotherapy agents or oncolytic viral therapies.

Benefits

Maximum treatment concentration at the tumor site with reduced general side effects.

Procedure

Under local anesthesia and ultrasound or CT guidance, a needle is introduced into the tumor and the therapeutic agent is injected. Multiple sessions may be needed.

Risks

Risks depend on tumor location and the agent used (local reaction, bleeding, infection).

Recovery and follow-up

Same-day discharge is generally possible. Follow-up is defined by the treatment protocol.

Practical information

Local anesthesia. Outpatient procedure (return home the same day).