Percutaneous Intralesional Therapeutic Agent Injection
Direct injection of a therapeutic agent into a tumor under image guidance.
Percutaneous Intralesional Therapeutic Agent Injection
Synonyms : image-guided intralesional injection, percutaneous intratumoral injection
Background and indications
Certain experimental or targeted anticancer treatments can be injected directly into a tumor to maximize local concentration while limiting systemic side effects. This includes local immunotherapy agents or oncolytic viral therapies.
Benefits
Maximum treatment concentration at the tumor site with reduced general side effects.
Procedure
Under local anesthesia and ultrasound or CT guidance, a needle is introduced into the tumor and the therapeutic agent is injected. Multiple sessions may be needed.
Risks
Risks depend on tumor location and the agent used (local reaction, bleeding, infection).
Recovery and follow-up
Same-day discharge is generally possible. Follow-up is defined by the treatment protocol.
Practical information
Local anesthesia. Outpatient procedure (return home the same day).
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